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van der Ven CF, Wu PJ, Tibbitt MW, van Mil A, Sluijter JP, Langer R, Aikawa E
In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease.
Clin Sci (Lond). 2017;131(3):181-195 - PMID: 28057890 - PMCID: PMC5459552 - DOI: 10.1042/CS20160378
Hutcheson JD, Blaser MC, Aikawa E
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field.
Circ Res. 2017;120(2):270-273 - PMID: 28104767 - PMCID: PMC5260841 - DOI: 10.1161/CIRCRESAHA.116.310060
Goettsch C, Iwata H, Hutcheson JD, O'Donnell CJ, Chapurlat R, Cook NR, Aikawa M, Szulc P, Aikawa E
Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.
Arterioscler Thromb Vasc Biol. 2017;37(5):1005-1011 - PMID: 28279970 - PMCID: PMC5407935 - DOI: 10.1161/ATVBAHA.116.308932
Nagy E, Lei Y, Martínez-Martínez E, Body SC, Schlotter F, Creager M, Assmann A, Khabbaz K, Libby P, Hansson GK, Aikawa E
Interferon-γ Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves.
Am J Pathol. 2017;187(6):1413-1425 - PMID: 28431214 - PMCID: PMC5455058 - DOI: 10.1016/j.ajpath.2017.02.012
Franck G, Mawson T, Sausen G, Salinas M, Santos Masson G, Cole AP, Beltrami Moreira M, Chatzizisis Y, Quillard T, Tesmenitsky Y, Shvartz E, Sukhova GK, Swirski FK, Nahrendorf M, Aikawa E, Croce K, Libby P
Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice - Implications for Superficial Erosion.
Circ Res. 2017;121(1):31-42 - PMID: 28428204 - PMCID: PMC5488735 - DOI: 10.1161/CIRCRESAHA.117.310694
Aikawa E, Libby P
A Rock and a Hard Place: Chiseling Away at the Multiple Mechanisms of Aortic Stenosis.
Circulation. 2017;135(20):1951-1955 - PMID: 28507250 - PMCID: PMC5479353 - DOI: 10.1161/CIRCULATIONAHA.117.027776
Rogers M, Maldonado-Martinez N, Hutcheson JD, Goettsch C, Goto S, Yamada I, Faits T, Sesaki H, Aikawa M, Aikawa E
Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.
Circ Res. 2017;121(3):220-233 - PMID: 28607103 - PMCID: PMC5546003 - DOI: 10.1161/CIRCRESAHA.116.310293
Rogers MA, Aikawa M, Aikawa E
Macrophage Heterogeneity Complicates Reversal of Calcification in Cardiovascular Tissues.
Circ Res. 2017;121(1):5-7 - PMID: 28642321 - PMCID: PMC5507366 - DOI: 10.1161/CIRCRESAHA.117.311219
Bartko PE, Dal-Bianco JP, Guerrero JL, Beaudoin J, Szymanski C, Kim DH, Seybolt MM, Handschumacher MD, Sullivan S, Garcia ML, Titus JS, Wylie-Sears J, Irvin WS, Messas E, Hagège AA, Carpentier A, Aikawa E, Bischoff J, Levine RA, Leducq Transatlantic Mitral Network
Effect of Losartan on Mitral Valve Changes After Myocardial Infarction.
J Am Coll Cardiol. 2017;70(10):1232-1244 - PMID: 28859786 - PMCID: PMC5679094 - DOI: 10.1016/j.jacc.2017.07.734
Le Tourneau T, Le Scouarnec S, Cueff C, Bernstein D, Aalberts JJJ, Lecointe S, Mérot J, Bernstein JA, Oomen T, Dina C, Karakachoff M, Desal H, Al Habash O, Delling FN, Capoulade R, Suurmeijer AJH, Milan D, Norris RA, Markwald R, Aikawa E, Slaugenhaupt SA, Jeunemaitre X, Hagège A, Roussel JC, Trochu JN, Levine RA, Kyndt F, Probst V, Le Marec H, Schott JJ
New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study.
Eur Heart J. 2017;39(15):1269-1277 - PMID: 29020406 - PMCID: PMC5905589 - DOI: 10.1093/eurheartj/ehx505
Beaudoin J, Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Sullivan S, Bartko PE, Handschumacher MD, Kim DH, Wylie-Sears J, Aaron J, Levine RA
Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling.
Circ Cardiovasc Imaging. 2017;10(11):ePub - PMID: 29042413 - PMCID: PMC5683411 - DOI: 10.1161/CIRCIMAGING.117.006512
Peeters FECM, Meex SJR, Dweck MR, Aikawa E, Crijns HJGM, Schurgers LJ, Kietselaer BLJH
Calcific aortic valve stenosis: hard disease in the heart: A biomolecular approach towards diagnosis and treatment.
Eur Heart J. 2017;:ePub
Goettsch C, Kjolby M, Aikawa E
Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases.
Arterioscler Thromb Vasc Biol. 2017;38(1):19-25 - PMID: 29191923 - PMCID: PMC5746432 - DOI: 10.1161/ATVBAHA.117.310292
Kim DH, Heo R, Handschumacher MD, Lee S, Choi YS, Kim KR, Shin Y, Park HK, Bischoff J, Aikawa E, Song JM, Kang DH, Levine RA, Song JK
Mitral Valve Adaptation to Isolated Annular Dilation: Insights Into the Mechanism of Atrial Functional Mitral Regurgitation.
JACC Cardiovasc Imaging. 2017;12(4):665-677 - PMID: 29248661 - PMCID: PMC5993562 - DOI: 10.1016/j.jcmg.2017.09.013
Bakhshian Nik A, Hutcheson JD, Aikawa E
Extracellular Vesicles As Mediators of Cardiovascular Calcification.
Front Cardiovasc Med. 2017;4:78 - PMID: 29322046 - PMCID: PMC5732140 - DOI: 10.3389/fcvm.2017.00078
Masoumi N, Copper D, Chen P, Cubberley A, Guo K, Lin RZ, Ahmed B, Martin D, Aikawa E, Melero-Martin J, Mayer J
Elastomeric Fibrous Hybrid Scaffold Supports In Vitro and In Vivo Tissue Formation.
Adv Funct Mater. 2017;27(27):ePub - PMID: 32863817 - PMCID: PMC7450820 - DOI: 10.1002/adfm.201606614
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