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Bartoli-Leonard F, Turner ME, Zimmer J, Chapurlat R, Pham T, Aikawa M, Pradhan AD, Szulc P, Aikawa E
Elevated lipoprotein(a) as a predictor for coronary events in older men.
J Lipid Res. 2022;63(8):100242 - PMID: 35724702 - PMCID: PMC9304778 - DOI: 10.1016/j.jlr.2022.100242
Sutton NR, Malhotra R, Hilaire CS, Aikawa E, Blumenthal RS, Gackenbach G, Goyal P, Johnson A, Nigwekar SU, Shanahan CM, Towler DA, Wolford BN, Chen Y
Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification.
Arterioscler Thromb Vasc Biol. 2022;:ePub - PMID: 36412195 - DOI: 10.1161/ATVBAHA.122.317332
Krohn JB, Aikawa E, Aikawa M, Hutcheson JD, Sahoo S, Fish JE
Editorial: Extracellular vesicles in cardiovascular inflammation and calcification.
Front Cardiovasc Med. 2022;9:1077124 - PMID: 36426218 - PMCID: PMC9680153 - DOI: 10.3389/fcvm.2022.1077124
Corti A, De Paolis A, Grossman P, Dinh PA, Aikawa E, Weinbaum S, Cardoso L
The effect of plaque morphology, material composition and microcalcifications on the risk of cap rupture: A structural analysis of vulnerable atherosclerotic plaques.
Front Cardiovasc Med. 2022;9:1019917 - PMID: 36277774 - PMCID: PMC9583261 - DOI: 10.3389/fcvm.2022.1019917
Kuo A, Checa A, Niaudet C, Jung B, Fu Z, Wheelock CE, Singh SA, Aikawa M, Smith LEH, Proia RL, Hla T
Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasi.
Elife. 2022;11:ePub - PMID: 36197001 - PMCID: PMC9578713 - DOI: 10.7554/eLife.78861
Morgan S, Lee LH, Halu A, Nicolau JS, Higashi H, Ha AH, Wen JR, Daugherty A, Libby P, Cameron SJ, Mix D, Aikawa E, Owens AP, Singh SA, Aikawa M
Identifying novel mechanisms of abdominal aortic aneurysm via unbiased proteomics and systems biology.
Front Cardiovasc Med. 2022;9:889994 - PMID: 35990960 - PMCID: PMC9382335 - DOI: 10.3389/fcvm.2022.889994
Atkins SK, Sonawane AR, Brouwhuis R, Barrientos J, Ha A, Rogers M, Tanaka T, Okui T, Kuraoka S, Singh SA, Aikawa M, Aikawa E
Induced pluripotent stem cell-derived smooth muscle cells to study cardiovascular calcification.
Front Cardiovasc Med. 2022;9:925777 - PMID: 35958427 - PMCID: PMC9357895 - DOI: 10.3389/fcvm.2022.925777
Uchida S, Yu J, Goldman M, Asmis R, Yang X, Aikawa E, Bourantas C, Aikawa M, Tevaearai Stahel H
Editorial: Research reproducibility and preventing fraud.
Front Cardiovasc Med. 2022;9:979467 - PMID: 35979020 - PMCID: PMC9376614 - DOI: 10.3389/fcvm.2022.979467
Marsit O, Clavel MA, Paquin A, Deschênes V, Hadjadj S, Sénéchal-Dumais I, Couet J, Arsenault M, Handschumacher MD, Levine RA, Aikawa E, Pibarot P, Beaudoin J
Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction.
J Am Coll Cardiol. 2022;80(5):500-510 - PMID: 35902173 - DOI: 10.1016/j.jacc.2022.05.025
Wang L, Xu GE, Pan L, Aikawa E, Aikawa M, Xiao J, Huang NF
Editorial: Frontiers in Cardiovascular Medicine: Rising Stars 2021.
Front Cardiovasc Med. 2022;9:928981 - PMID: 35757336 - PMCID: PMC9218798 - DOI: 10.3389/fcvm.2022.928981
Asano T, Chelvanambi S, Decano JL, Whelan MC, Aikawa E, Aikawa M
In silico Drug Screening Approach Using L1000-Based Connectivity Map and Its Application to COVID-19.
Front Cardiovasc Med. 2022;9:842641 - PMID: 35402570 - PMCID: PMC8989014 - DOI: 10.3389/fcvm.2022.842641
Decano JL, Iwamoto Y, Goto S, Lee JY, Matamalas JT, Halu A, Blaser M, Lee LH, Pieper B, Chelvanambi S, Silva-Nicolau J, Bartoli-Leonard F, Higashi H, Shibata H, Vyas P, Wang J, Gostjeva E, Body SC, Singh SA, Aikawa M, Aikawa E
A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling.
Cell Rep. 2022;39(2):110685 - PMID: 35417712 - DOI: 10.1016/j.celrep.2022.110685
Paquin A, Marsit O, Deschênes V, Rouabhia D, Hadjadj S, Clisson M, Robitaille C, Aikawa E, Levine RA, Pibarot P, Clavel MA, Beaudoin J
Progression of aortic stenosis after an acute myocardial infarction.
Open Heart. 2022;9(1):ePub - PMID: 35728891 - PMCID: PMC9214429 - DOI: 10.1136/openhrt-2022-002046
Human P, Bezuidenhout D, Aikawa E, Zilla P
Residual Bioprosthetic Valve Immunogenicity: Forgotten, Not Lost.
Front Cardiovasc Med. 2022;8:760635 - PMID: 35059444 - PMCID: PMC8764456 - DOI: 10.3389/fcvm.2021.760635
Sonawane AR, Aikawa E, Aikawa M
Connections for Matters of the Heart: Network Medicine in Cardiovascular Diseases.
Front Cardiovasc Med. 2022;9:873582 - PMID: 35665246 - PMCID: PMC9160390 - DOI: 10.3389/fcvm.2022.873582
Dacano JL, Aikawa M, Singh SA
Promise of a Novel Bedside-to-Bench Paradigm: Can Percutaneous Coronary Intervention Proteomics Balloon Into Clinical Practice?
Arterioscler Thromb Vasc Biol. 2022;42(7):865-867 - PMID: 35616034 - DOI: 10.1161/ATVBAHA.122.317802
Garelnabi M, Cowdin M, Fang Y, Shrestha B, Ushio-Fukai M, Aikawa E, Graham G, Molema G, Yanagisawa H, Aikawa M
Embracing Diversity, Equity, and Inclusion in the Scientific Community-Viewpoints of the Diversity, Equity, and Inclusion Committee of the North American Vascular Biology Organization.
Front Cardiovasc Med. 2022;9:863256 - PMID: 35463765 - PMCID: PMC9021758 - DOI: 10.3389/fcvm.2022.863256
Aikawa E, Hutcheson JD
The Developmental Origin of Calcific Aortic Stenosis.
N Engl J Med. 2022;386(14):1372-1374 - PMID: 35388675 - DOI: 10.1056/NEJMcibr2200439
Gomes NFA, Silva VR, Levine RA, Esteves WAM, de Castro ML, Passos LSA, Dal-Bianco JP, Pantaleão AN, da Silva JLP, Tan TC, Dutra WO, Aikawa E, Hung J, Nunes MCP
Progression of Mitral Regurgitation in Rheumatic Valve Disease: Role of Left Atrial Remodeling.
Front Cardiovasc Med. 2022;9:862382 - PMID: 35360029 - PMCID: PMC8962951 - DOI: 10.3389/fcvm.2022.862382
Alvandi Z, Nagata Y, Passos LSA, Hashemi Gheinani A, Guerrero JL, Wylie-Sears J, Romero DC, Morris BA, Sullivan SM, Yaghoubian KM, Alvandi A, Adam RM, Aikawa E, Levine RA, Bischoff J
Wnt Site Signaling Inhibitor Secreted Frizzled-Related Protein 3 Protects Mitral Valve Endothelium From Myocardial Infarction-Induced Endothelial-to-Mesenchymal Transition.
J Am Heart Assoc. 2022;11(7):e023695 - PMID: 35348006 - PMCID: PMC9075477 - DOI: 10.1161/JAHA.121.023695
Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG
Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles.
Cardiovasc Res. 2022;:ePub - PMID: 35325061 - DOI: 10.1093/cvr/cvac031
Passos LSA, Jha PK, Becker-Greene D, Blaser MC, Romero D, Lupieri A, Sukhova GK, Libby P, Singh SA, Dutra WO, Aikawa M, Levine RA, Nunes MCP, Aikawa E
Prothymosin Alpha: A Novel Contributor to Estradiol Receptor Alpha-Mediated CD8+ T-Cell Pathogenic Responses and Recognition of Type 1 Collagen in Rheumatic Heart Valve Disease.
Circulation. 2022;145(7):531-548 - PMID: 35157519 - PMCID: PMC8869797 - DOI: 10.1161/CIRCULATIONAHA.121.057301
Rogers MA, Atkins SK, Zheng KH, Singh SA, Chelvanambi S, Pham TH, Kuraoka S, Stroes ESG, Aikawa M, Aikawa E
Lipoprotein(a) Induces Vesicular Cardiovascular Calcification Revealed With Single-Extracellular Vesicle Analysis.
Front Cardiovasc Med. 2022;9:778919 - PMID: 35155626 - PMCID: PMC8831739 - DOI: 10.3389/fcvm.2022.778919
Sawada H, Katsumata Y, Higashi H, Zhang C, Li Y, Morgan S, Lee LH, Singh SA, Chen JZ, Franklin MK, Moorleghen JJ, Howatt DA, Rateri DL, Shen YH, LeMaire SA, Aikawa M, Majesky MW, Lu HS, Daugherty A
Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies.
Circulation. 2022;145(13):987-1001 - PMID: 35143327 - PMCID: PMC9008740 - DOI: 10.1161/CIRCULATIONAHA.121.058173
Buffolo F, Monticone S, Camussi G, Aikawa E
Role of Extracellular Vesicles in the Pathogenesis of Vascular Damage.
Hypertension. 2022;79(5):863-873 - PMID: 35144490 - PMCID: PMC9010370 - DOI: 10.1161/HYPERTENSIONAHA.121.17957
Tanaka T, Asano T, Okui T, Kuraoka S, Singh SA, Aikawa M, Aikawa E
Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification.
Front Cardiovasc Med. 2022;8:826529 - PMID: 35127876 - PMCID: PMC8811128 - DOI: 10.3389/fcvm.2021.826529
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