Our History and Mission

Group

The Center for Interdisciplinary Cardiovascular Sciences (CICS) was established in 2009 by a collaboration agreement between the Brigham and Women’s Hospital (Boston, MA) and Kowa Company, Ltd. (Tokyo, Japan).

The goals of CICS are to promote better understanding of the mechanisms of cardiovascular inflammation and cardiometabolic disorders and to enhance further advancement in cardiovascular prevention and therapy through a translational research program that consists of investigators from academia and industry with multidisciplinary backgrounds acting in concert in a shared space.

Featured Scientist

Dr. Maximillian (Max) Rogers

Dr. Maximillian (Max) Rogers

Dr. Maximillian (Max) Rogers joined CICS in the summer of 2012 as a research fellow in Dr. Elena Aikawa’s Vascular biology, Valve disease & Calcification Group.

Max obtained his PhD in Biochemistry through the Molecular and Cell Biology program at Dartmouth. He then received a NIH NRSA postdoctoral fellowship and briefly worked as a faculty research fellow examining cholesterol metabolism and human disease before coming to CICS.

At CICS he is identifying novel targets for cardiovascular calcification and lipid metabolism, with a primary focus on the role of DRP1 and mitochondrial dynamics in cardiovascular disease. To accomplish this goal he uses human clinical tissues, animal and cell models, and a variety of biochemical and molecular biology tools including: CRISPR, AAV, RNAi, qPCR, ELISA and western blotting, SILAC mass spectrometry, histology, confocal immunofluorescence, electron microscopy, and small molecule PK/PD studies.

Max has presented his work at AHA Scientific Sessions, ISACB, and EAS annual meetings, and has won young investigator awards from both AHA and EAS. Recently he received his fourth patent for his CICS work identifying a novel small molecule means of inhibiting PCSK9. An avid reader of scientific literature, he enjoys discussing biomedical science in a wide range of fields, and is happy to discuss the opportunities available in Boston’s Longwood area.

News

2017-06-12:

Maximillian Rogers,Ph.D 's paper "the DRP1 and calcification" has been published on the Circulation Research .

2017-05-16:

Masanori Aikawa,MD, Ph.D moderated at World Medical Innovation Forum 2017, the Special Focus Session “Japan Today”. Here is a link to the Japan session on this YouTube channel.

2017-05-01:

Elena Aikawa kicked off the Word Medical Innovation Forum in Boston today by promoting her Heart Valve Translational Research Program at Brigham and Women's Hospital. Go Elena!

2016-10-04:

Masanori Aikawa,MD, Ph.D became Chief Editor of Frontiers in Cardiovascular Medicine.

2016-09-30:

Celebrating Women in Women in Medicine and Science (WMSS)’s fifth year, the symposium was co-sponsored by the BWH Center for Faculty Development and Diversity (CFDD), the Brigham Research Institute, the Center for Clinical Investigation and the Connors Center for Women’s Health and Gender Biology. Elena Aikawa,MD, Ph.D the event founder and co-chair, noted the symposium provides an opportunity for clinicians and researchers from various disciplines—whose paths may not ordinarily cross—to learn about their colleagues’ work. Sited from the (Past News)