Our History and Mission


The Center for Interdisciplinary Cardiovascular Sciences (CICS) was established in 2009 by a collaboration agreement between the Brigham and Women’s Hospital (Boston, MA) and Kowa Company, Ltd. (Tokyo, Japan).

The goals of CICS are to promote better understanding of the mechanisms of cardiovascular inflammation and cardiometabolic disorders and to enhance further advancement in cardiovascular prevention and therapy through a translational research program that consists of investigators from academia and industry with multidisciplinary backgrounds acting in concert in a shared space.

Featured Scientist

Dr. Lang Ho Lee

Dr. Lang Ho Lee

Dr. Lang Ho Lee joined CICS in the summer of 2015 as a research fellow in Dr. Sasha Singh’s proteomics and bioinformatics group. Lang studied the life sciences and computer science at Handong University (South Korea), and then obtained his Master’s degree in biomedical database construction at Yonsei University. Lang moved to the United States to pursue his PhD studies in bioinformatics and statistics in a joint program between the University of Tennessee and Oak Ridge National Laboratory. At CICS he is developing tools for various types of big biology data including RNA-Seq, and targeted and global proteomics data. Lang has expertise in Python and R programming as well as biostatistics that he uses to facilitate basic research and clinical studies. He published his software for extracting PRM peak Intensities (XPI) for in vivo metabolism studies in Proteomics in early 2017. Lang has presented his work at ASMS, US-HUPO and IVBM annual meetings. He also won the 2017 CICS Innovation Award, as selected by his CICS peers. He enjoys working with researchers and learning new technologies.



Congratulations to Dr. Elena Aikawa for receiving a Harvard Catalyst Reactor Grant for exploring effective drug treatments for calcific aortic valve disease, through 3D printing technologies!


We had Ana and Aline's farewell. Good luck with your school, Ana and Aline!


Maximillian Rogers,Ph.D 's paper "the DRP1 and calcification" has been published on the Circulation Research .


Masanori Aikawa,MD, Ph.D moderated at World Medical Innovation Forum 2017, the Special Focus Session “Japan Today”. Here is a link to the Japan session on this YouTube channel.


Elena Aikawa kicked off the Word Medical Innovation Forum in Boston today by promoting her Heart Valve Translational Research Program at Brigham and Women's Hospital. Go Elena!

(Past News)