Our History and Mission


The Center for Interdisciplinary Cardiovascular Sciences (CICS) was established in 2009 by a collaboration agreement between the Brigham and Women’s Hospital (Boston, MA) and Kowa Company, Ltd. (Tokyo, Japan).

The goals of CICS are to promote better understanding of the mechanisms of cardiovascular inflammation and cardiometabolic disorders and to enhance further advancement in cardiovascular prevention and therapy through a translational research program that consists of investigators from academia and industry with multidisciplinary backgrounds acting in concert in a shared space.

Featured Scientist

Dr. Florian Schlotter

Dr. Florian Schlotter

Dr. Florian Schlotter is a research fellow in Dr. Elena Aikawa’s Vascular Biology and Cardiovascular Calcification Research Group. His primary scientific interest, and focus of research at CICS, is valvular heart disease. In 2012, Florian graduated from the Medical School of the University of Leipzig, Germany and began his residency training and fellowship in cardiology at the Heart Center Leipzig. Florian’s broad knowledge in OMICs techniques, cardiovascular imaging, and in vitro and in vivo models helped him to define the first Molecular Atlas of Calcific Aortic Valve Disease. This work, that was completed with CICS’s multi-talented team, was recently published in Circulation. His additional projects include the identification of calcification-related signaling mechanisms in valve cells and multi-modality imaging of the aortic valve. Florian enjoys cycling and sailing around Boston, participating in triathlons, and exploring New England together with his family.



CICS study looking at sortilin regulation of cholesterol absorption and obesity has been published in


The 3rd Aortic Valve Symposium at BWH will be held on April 12 from 3 pm to 7 pm. Location CICS, CLSB, Floor 17. Contact Dr. Elena Aikawa at eaikawa@bwh.harvard.edu. Please see the program for details.


Dr. Elena Aikawa ‘s First Look Arcicles is on the BWH Bridges, Partners Innovation Blog.


Congratulations to Dr. Elena Aikawa for receiving a Harvard Catalyst Reactor Grant for exploring effective drug treatments for calcific aortic valve disease, through 3D printing technologies!

(Past News)


2018-05-02 CICS Seminar
Kenneth Walsh, PhD

2018-04-25 CICS Seminar
Andrew Hopkins, PhD

2018-04-12 CICS Seminar
Katherine E. Yutzey, PhD

2018-04-12 Heart Valve Translational Research Program Symposium

(Past Events)