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Halu A, Chelvanambi S, Decano JL, Matamalas JT, Whelan M, Asano T, Kalicharran N, Singh SA, Loscalzo J, Aikawa M

Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery.
Genome Med. 2025;17(1):7 - PMID: 39833831 - PMCID: PMC11744892 - DOI: 10.1186/s13073-025-01431-x

Bhattacharjee S, Gao J, Lu YW, Eisa-Beygi S, Wu H, Li K, Birsner AE, Wong S, Song Y, Shyy JY, Cowan DB, Huang W, Wei W, Aikawa M, Shi J, Chen H

Endothelial FOXM1 and Dab2 promote diabetic wound healing.
JCI Insight. 2025;10(2):ePub - PMID: 39846251 - PMCID: PMC11790024 - DOI: 10.1172/jci.insight.186504

Boucher DM, Robichaud S, Lorant V, Leon JS, Suliman I, Rasheed A, Susser LI, Emerton C, Geoffrion M, De Jong E, Bowdish DME, Aikawa M, Aikawa E, Singh SA, Rayner KJ, Ouimet M

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression.
Arterioscler Thromb Vasc Biol. 2025;45(4):481-495 - PMID: 39945065 - PMCID: PMC11936474 - DOI: 10.1161/ATVBAHA.124.321662

Lansac E, Veen KM, Joseph A, Jaber PB, Sossi F, Das-Gupta Z, Aktaa S, Rafael Sádaba J, Thourani VH, Dahle G, Szeto WY, Bakaeen F, Aikawa E, Schoen FJ, Girdauskas E, Almeida A, Zuckermann A, Meuris B, Stott J, Kluin J, Meel R, Woan W, Colgan D, Jneid H, Balkhy H, Szerlip M, Preventza O, Shah P, Rigolin VH, Medica S, Holmes P, Sitges M, Pibarot P, Donal E, Hahn RT, Takkenberg JJM

The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes.
Eur J Cardiothorac Surg. 2025;67(2):ePub - PMID: 39957685 - PMCID: PMC11842054 - DOI: 10.1093/ejcts/ezae254

Lansac E, Veen KM, Joseph A, Jaber PB, Sossi F, Das-Gupta Z, Aktaa S, Sádaba JR, Thourani VH, Dahle G, Szeto WY, Bakaeen F, Aikawa E, Schoen FJ, Girdauskas E, Almeida A, Zuckermann A, Meuris B, Stott J, Kluin J, Meel R, Woan W, Colgan D, Jneid H, Balkhy H, Szerlip M, Preventza O, Shah P, Rigolin VH, Medica S, Holmes P, Sitges M, Pibarot P, Donal E, Hahn RT, Takkenberg JJM

The first International Consortium for Health Outcomes Measurement (ICHOM) standard dataset for reporting outcomes in heart valve disease: moving from device- to patient- centered outcomes.
Eur Heart J Qual Care Clin Outcomes. 2025;11(5):515-528 - PMID: 39957667 - PMCID: PMC12342911 - DOI: 10.1093/ehjqcco/qcae051

Lansac E, Veen KM, Joseph A, Blancarte Jaber P, Sossi F, Das-Gupta Z, Aktaa S, Sádaba JR, Thourani VH, Dahle G, Szeto WY, Bakaeen F, Aikawa E, Schoen FJ, Girdauskas E, Almeida A, Zuckermann A, Meuris B, Stott J, Kluin J, Meel R, Woan W, Colgan D, Jneid H, Balkhy H, Szerlip M, Preventza O, Shah P, Rigolin VH, Medica S, Holmes P, Sitges M, Pibarot P, Donal E, Hahn RT, Takkenberg JJM

The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes.
Circ Cardiovasc Qual Outcomes. 2025;18(3):e000128 - PMID: 39957624 - PMCID: PMC11917533 - DOI: 10.1161/HCQ.0000000000000128

Lansac E, Veen KM, Joseph A, Blancarte Jaber P, Sossi F, Das-Gupta Z, Aktaa S, Sádaba JR, Thourani VH, Dahle G, Szeto WY, Bakaeen F, Aikawa E, Schoen FJ, Girdauskas E, Almeida A, Zuckermann A, Meuris B, Stott J, Kluin J, Meel R, Woan W, Colgan D, Jneid H, Balkhy H, Szerlip M, Preventza O, Shah P, Rigolin VH, Medica S, Holmes P, Sitges M, Pibarot P, Donal E, Hahn RT, Takkenberg JJM

The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes: Developed by a multisociety taskforce coordinated by the Heart Valve Society (HVS) including the American Heart Association (AHA), the American College of Cardiology (ACC), the European Association for Cardio-Thoracic Surgery (EACTS), the European Society of Cardiology (ESC), The Society of Thoracic Surgeons (STS), the Australian & New Zealand Society of Cardiac & Thoracic Surgeons (ANZSCTS), the International Society for Applied Cardiovascular Biology (ISACB), the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS), the South African Heart Association (SHA), Heart Valve Voice, and Global Heart Hub.
JACC Adv. 2025;4(4):101059 - PMID: 39966045 - PMCID: PMC12139239 - DOI: 10.1016/j.jacadv.2024.101059

Lansac E, Veen KM, Joseph A, Blancarte Jaber P, Sossi F, Das-Gupta Z, Aktaa S, Sádaba JR, Thourani VH, Dahle G, Szeto WY, Bakaeen F, Aikawa E, Schoen FJ, Girdauskas E, Almeida A, Zuckermann A, Meuris B, Stott J, Kluin J, Meel R, Woan W, Colgan D, Jneid H, Balkhy H, Szerlip M, Preventza O, Shah P, Rigolin VH, Medica S, Holmes P, Sitges M, Pibarot P, Donal E, Hahn RT, Takkenberg JJM

The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes.
Innovations (Phila). 2025;20(2):133-147 - PMID: 39968696 - PMCID: PMC12089684 - DOI: 10.1177/15569845241269309

Aikawa E, Allison MA, Iruela Arispe L, Bendeck MP, Chen Y, Gardiner EE, Golledge J, Suzuki-Inoue K, Marelli-Berg F, Powell JT, Ramasamy R, Sarpong DF, Sorci-Thomas MG, Daugherty A, Hegele RA, Schmidt AM

Honoring the Life and Legacy of Dr David A. Dichek.
Arterioscler Thromb Vasc Biol. 2024;44(7):1459-1461 - PMID: 40030047 - DOI: 10.1161/ATVBAHA.124.321293

Boeck M, Yagi H, Chen CT, Zeng Y, Lee D, Nian S, Kasai T, Lee J, Hirst V, Wang C, Neilsen K, Rodrick TC, McCutcheon A, Yu M, Lodhi IJ, Singh SA, Aikawa M, Bazinet RP, Fu Z

Nutrient supplementation mitigates retinal dysfunction in Acox1 knockout mice with impaired peroxisomal fatty acid oxidation.
J Adv Res. 2025;78:667-680 - PMID: 40049514 - PMCID: PMC12684955 - DOI: 10.1016/j.jare.2025.03.004

Lansac E, Veen KM, Joseph A, Jaber PB, Sossi F, Das-Gupta Z, Aktaa S, Sádaba JR, Thourani VH, Dahle G, Szeto WY, Bakaeen F, Aikawa E, Schoen FJ, Girdauskas E, Almeida A, Zuckermann A, Meuris B, Stott J, Kluin J, Meel R, Woan W, Colgan D, Jneid H, Balkhy H, Szerlip M, Preventza O, Shah P, Rigolin VH, Medica S, Holmes P, Sitges M, Pibarot P, Donal E, Hahn RT, Takkenberg JJM

The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes: Developed by a multisociety taskforce coordinated by the Heart Valve Society (HVS) including the American Heart Association (AHA), the American College of Cardiology (ACC), the European Association for Cardio-Thoracic Surgery (EACTS), the European Society of Cardiology (ESC), The Society of Thoracic Surgeons (STS), the Australian & New Zealand Society of Cardiac & Thoracic Surgeons (ANZSCTS), the International Society for Applied Cardiovascular Biology (ISACB), the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS), the South African Heart Association (SHA), Heart Valve Voice, and Global Heart Hub.
Ann Thorac Surg Short Rep. 2025;3(1):71-85 - PMID: 40098847 - PMCID: PMC11910787 - DOI: 10.1016/j.atssr.2024.05.005

Song N, Ji E, Yu JE, Choi KH, Kim DH, Song JM, Kang DH, Song JK, Yu J, Kim K, Lee S, Aikawa E

Spermidine Enhances Mitochondrial Function and Mitigates Aortic Valve Calcification: Implications for DNA Methyltransferase-1 Activity.
JACC Basic Transl Sci. 2025;10(3):345-366 - PMID: 40139876 - PMCID: PMC12013848 - DOI: 10.1016/j.jacbts.2024.11.011

Lupieri A, Jha PK, Nizet V, Dutra WO, Nunes MCP, Levine RA, Aikawa E

Rheumatic heart valve disease: navigating the challenges of an overlooked autoimmune disorder.
Front Cardiovasc Med. 2025;12:1537104 - PMID: 40182432 - PMCID: PMC11966398 - DOI: 10.3389/fcvm.2025.1537104

Jha PK, Nakano T, Itto LYU, Barbeiro MC, Lupieri A, Aikawa E, Aikawa M

Vascular inflammation in chronic kidney disease: the role of uremic toxins in macrophage activation.
Front Cardiovasc Med. 2025;12:1574489 - PMID: 40201789 - PMCID: PMC11975941 - DOI: 10.3389/fcvm.2025.1574489

Bortolin RH, de Souza Leite F, Luchessi AD, Esposito J, Barbosa IN, Costa de Freitas RC, Sonawane AR, Singh SA, Aikawa E, Silva KAT, Hirata TDC, Neta APR, Goulart E, Caires-Júnior LC, Mata Martins TMD, Semedo P, de Paula Moreira D, Naslavsky M, Faludi AA, Gonçalves RM, Araujo DB, Malaquias VB, Ferreira GM, DeOcesano-Pereira C, Chudzinski-Tavassi AM, Pu WT, Zatz M, Hirata RDC, Hirata MH

Translational insights into statin-induced myotoxicity: differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia.
Toxicology. 2025;515:154159 - PMID: 40254247 - DOI: 10.1016/j.tox.2025.154159

Jung B, Yagi H, Kuo A, Dorweiler TF, Aikawa M, Kasai T, Singh SA, Dannenberg AJ, Fu Z, Niaudet C, Smith LEH, Hla T

ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage.
Angiogenesis. 2025;28(2):24 - PMID: 40266369 - PMCID: PMC12018641 - DOI: 10.1007/s10456-025-09975-7

Yagi H, Qiu C, Zeng Y, Boeck M, Nian S, Chen CT, Harman JC, Kasai T, Lee J, Hirst V, Neilsen K, Wang C, Bora K, Maurya M, Rodrick T, Grumbine M, Yang Y, Hua Z, Sweet IR, Singh SA, Aikawa M, Chen J, Fu Z

Serine supplementation suppresses hypoxia-induced pathological retinal angiogenesis.
Theranostics. 2025;15(11):5087-5105 - PMID: 40303351 - PMCID: PMC12036884 - DOI: 10.7150/thno.105299

Lupieri A, Aikawa E

Decoding calcific aortic valve disease: is liver X receptor the key to lipid metabolism?
Cardiovasc Res. 2025;121(6):844-846 - PMID: 40389228 - DOI: 10.1093/cvr/cvaf080

Raju S, Turner ME, Cao C, Abdul-Samad M, Punwasi N, Blaser MC, Cahalane RME, Botts SR, Prajapati K, Patel S, Wu R, Gustafson D, Galant NJ, Fiddes L, Chemaly M, Hedin U, Matic L, Seidman MA, Subasri V, Singh SA, Aikawa E, Fish JE, Howe KL

Multiomic Landscape of Extracellular Vesicles in Human Carotid Atherosclerotic Plaque Reveals Endothelial Communication Networks.
Arterioscler Thromb Vasc Biol. 2025;45(7):1277-1305 - PMID: 40438929 - PMCID: PMC12188822 - DOI: 10.1161/ATVBAHA.124.322324

Higuita ML, Ajenu EO, Bolger-Chen M, Olverson G, Akbari Ghavimi SA, Lee SY, Kasai T, Michaud W, Chijioke C, Ruidas B, Pitti A, Minie N, Catricala J, Vincent D, Li S, D'Alessandro D, Aikawa E, Singh SA, Billaud M, Osho AA, Tessier SN, Rabi SA

Alternative preservation strategies of DCD hearts: Effect of cold ischemia time before normothermic machine perfusion.
medRxiv. 2025;:ePub - PMID: 40502597 - PMCID: PMC12154999 - DOI: 10.1101/2025.06.04.25329001

Lupieri A, Becker-Greene D, Le TD, Roschel MM, Jha PK, Sonawane AR, Mullick A, Tsimikas S, Kuraoka S, Singh SA, Aikawa M, Aikawa E

Antisense Oligonucleotide Targeting Sortilin Reduces Vascular Calcification in Mice in a Sex-Dependent Manner.
Arterioscler Thromb Vasc Biol. 2025;45(8):1398-1415 - PMID: 40501380 - PMCID: PMC12503371 - DOI: 10.1161/ATVBAHA.124.321999

Weiss L, Aikawa E

Glycolysis hijacked: a novel pathogenic role of lipoprotein(a) in valve disease.
Eur Heart J Open. 2025;5(4):oeaf069 - PMID: 40654528 - PMCID: PMC12246370 - DOI: 10.1093/ehjopen/oeaf069

Cahalane RME, Meuris B, Matamalas JT, Blaser MC, Billaud M, Kasai T, Hendrickx A, Goeminne LJE, Muehlschlegel J, Rega F, Aikawa M, McNamara L, Singh SA, Clift CL, Aikawa E

Cross-species proteomics quantification pipeline distinguishes donor versus host extracellular matrix in explanted biomaterials.
bioRxiv. 2025;:ePub - PMID: 40667106 - PMCID: PMC12262681 - DOI: 10.1101/2025.06.24.661315

Boeck M, Yagi H, Lundgren P, Pivodic A, Nilsson AK, Zeng Y, Chen CT, Kasai T, Lee D, Nian S, Hirst V, Neilsen K, Wang C, Lee J, Yu M, McCutcheon A, Singh SA, Aikawa M, Bazinet RP, Fu Z, Hellström A, Smith LE

Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice.
Pharmacol Res. 2025;219:107877 - PMID: 40706777 - PMCID: PMC12445345 - DOI: 10.1016/j.phrs.2025.107877

Delwarde C, Matamalas JT, Chelvanambi S, Kasai T, Shlayen G, Santinelli-Pestana DV, Zamani M, Aikawa E, Aikawa M, Singh SA

Nanoparticle-enabled plasma proteomics of a mouse atherosclerosis model.
bioRxiv. 2025;:ePub - PMID: 40766711 - PMCID: PMC12324543 - DOI: 10.1101/2025.08.01.667173

Chelvanambi S, Chen H, De Vries MR, Fang Y, Fredman G, Gomez D, Iwata H, Uchida S, Yanagisawa H, Aikawa M

Editorial: New trends in vascular biology 2024.
Front Cardiovasc Med. 2025;12:1649558 - PMID: 40777568 - PMCID: PMC12328353 - DOI: 10.3389/fcvm.2025.1649558

Clift CL, Goudot G, Bogut G, Kasai T, van Kampen A, Negrao Pantaleao A, Messas E, Aikawa M, Singh SA, Levine RA, Pernot M, Aikawa E

Short- and Long-Term Effects of Pulsed Ultrasound Cavitation Therapy of Calcified Valvular Interstitial Cells in Culture.
Ultrasound Med Biol. 2025;51(11):1936-1944 - PMID: 40796501 - DOI: 10.1016/j.ultrasmedbio.2025.06.026

Jha PK, Aikawa M, Aikawa E

Indoxyl sulfate: fuelling cardiovascular inflammation and calcification.
Cardiovasc Res. 2025;121(11):1642-1644 - PMID: 40795292 - PMCID: PMC12477674 - DOI: 10.1093/cvr/cvaf134

Sun J, Aikawa M, Ashktorab H, Beckmann ND, Enger ML, Espinosa JM, Gai X, Horne BD, Keim P, Lasky-Su J, Letts R, Maier CL, Mandal M, Nichols L, Roan NR, Russell MW, Rutter J, Saade GR, Sharma K, Shiau S, Thibodeau SN, Yang S, Miele L, NIH Researching COVID to Enhance Recovery (RECOVER) Consortium

A multi-omics strategy to understand PASC through the RECOVER cohorts: a paradigm for a systems biology approach to the study of chronic conditions.
Front Syst Biol. 2025;4:1422384 - PMID: 40809128 - PMCID: PMC12342036 - DOI: 10.3389/fsysb.2024.1422384

Clift CL, Blaser MC, Bartoli-Leonard F, Schlotter F, Higashi H, Kuraoka S, Kasai T, Turner ME, Pham T, Perez KA, Robson SC, Body SC, Muehlschlegel JD, Aikawa M, Singh SA, Aikawa E

Sexual Dimorphism of Plasma and Tissue Proteomes in Human Calcific Aortic Valve Stenosis Pathogenesis.
Arterioscler Thromb Vasc Biol. 2025;45(10):1928-1934 - PMID: 40808650 - DOI: 10.1161/ATVBAHA.125.322560

Goody PR, Christmann D, Goody D, Hildebrand S, Billig H, Nehl D, Chennupati R, Gladka M, Wilhelm-Jüngling K, Uchida S, Iris-Bibli S, Moore JB, Hamdani N, Paneni F, Pullamsetti SS, Zimmer S, Jansen F, Bakhtiary F, Aikawa E, Pfeifer A, Nickenig G, Hosen MR

Calcific aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk.
Basic Res Cardiol. 2025;120(5):991-1010 - PMID: 40847220 - PMCID: PMC12518376 - DOI: 10.1007/s00395-025-01133-w

Santinelli-Pestana DV, Delwarde C, Kasai T, Kuraoka S, Nakamura Y, Okada T, Decano JL, Chelvanambi S, Ge R, Mlynarchik AK, Perez K, Campedelli A, Sonawane AR, Aikawa E, Singh SA, Aikawa M

ADP-Ribosylation in Experimental Atherosclerosis: A Potential Link Between Dyslipidemia and Inflammation in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2025;45(11):2137-2139 - PMID: 40905119 - PMCID: PMC12542996 - DOI: 10.1161/ATVBAHA.125.322497

Parthasarathy S, Saenjamsai P, Hao H, Ferkul A, Pfannenstiel JJ, Bejan DS, Chen Y, Suder EL, Schwarting N, Aikawa M, Muhlberger E, Hume AJ, Orozco RC, Sullivan CS, Cohen MS, Davido DJ, Fehr AR

PARP14 is an interferon-induced host factor that promotes IFN production and affects the replication of multiple viruses.
mBio. 2025;16(10):e0229925 - PMID: 40937852 - PMCID: PMC12505956 - DOI: 10.1128/mbio.02299-25

Song N, Yu J, Ji E, Yoon J, Choi KH, Yu JE, Kim B, Kim J, Kim M, Lee S, Kim K, Aikawa E

Characterization of Proteome Features in Patients With Aortic Stenosis Using Data-Independent Acquisition-Based Proteomic Analysis.
Korean Circ J. 2025;56(1):80-96 - PMID: 41044724 - PMCID: PMC12834629 - DOI: 10.4070/kcj.2025.0137

Jha PK, Chelvanambi S, Nakamura Y, Itto LYU, Vijay A, Lupieri A, Barbeiro MC, Le TD, Nascimento CB, Kasai T, Whelan MC, Hosokawa D, Becker-Greene D, Singh SA, Aikawa E, Uchida S, Aikawa M

A systems approach to target discovery identifies the role of lncRNA-SPANXA2-OT1 in macrophage chemotaxis.
JCI Insight. 2025;10(21):ePub - PMID: 41066194 - PMCID: PMC12643516 - DOI: 10.1172/jci.insight.191274

Hall IF, Aikawa E, Sluimer J, Baker AH, Kovacic JC

Endothelial to mesenchymal transition in cardiovascular diseases: molecular insights and clinical perspectives.
Eur Heart J. 2025;47(10):1144-1158 - PMID: 41128016 - PMCID: PMC13016786 - DOI: 10.1093/eurheartj/ehaf670

Yao J, Farrar CT, Aikawa E, Sosnovik DE, Moon BF, Kulkarni A, Ackerman JL

Ex Vivo Phosphorus-31 Solid State Magnetic Resonance Spectroscopy Identifies Compositional Differences Between Bone Mineral and Calcified Vascular Tissues.
medRxiv. 2025;:ePub - PMID: 41256110 - PMCID: PMC12622083 - DOI: 10.1101/2025.09.27.25336805

Mutarelli A, Pantaleao AN, Melo PHC, Nogueira W, Nogueira A, Felix N, Generoso G, Cardoso R, Lupieri A, Aikawa E, Levine RA, Nunes MCP

Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis.
Front Cardiovasc Med. 2025;12:1615158 - PMID: 41282342 - PMCID: PMC12631635 - DOI: 10.3389/fcvm.2025.1615158

Tun SC, Tin P, Aikawa M, Kobayashi I, Zin TT

Cattle lameness detection using depth image and deep learning.
Sci Rep. 2026;16(1):ePub - PMID: 41826368 - PMCID: PMC13111633 - DOI: 10.1038/s41598-026-40780-4

Kasai T, Weiss L, Wohlfahrt J, Matamalas JT, Shlayen G, Kirsch ZJ, Aikawa M, Aikawa E, Singh SA

Impact of Variations in Commercial Standard Operating Procedure on Plasma Proteome Recovery.
J Proteome Res. 2026;25(4):1941-1950 - PMID: 41879802 - PMCID: PMC13054859 - DOI: 10.1021/acs.jproteome.5c01012

Chelvanambi S, Bernhagen J, Fredman G, Labarrere CA, Winkels H, Aikawa M

Editorial: Immunity, atherosclerosis, and cardiovascular disease: an interdisciplinary approach to cardiometabolic health.
Front Cardiovasc Med. 2026;13:1787241 - PMID: 41878482 - PMCID: PMC13006318 - DOI: 10.3389/fcvm.2026.1787241

Yuan XM, Singh SA

Editorial: Proteomics in atherosclerosis.
Front Cardiovasc Med. 2026;13:1792281 - PMID: 41969690 - PMCID: PMC13065504 - DOI: 10.3389/fcvm.2026.1792281

Matienzo N, Kress Z, Singh SA, Aikawa M, Soni RK, Li Y, Reyes-Soffer G

Comparative Proteomic Analysis of Lipoprotein(a): Method-Dependent Profiles and Disease Pathways.
J Clin Med. 2026;15(7):ePub - PMID: 41976861 - PMCID: PMC13073900 - DOI: 10.3390/jcm15072559

Itagawa R, Okui T, Tanaka T, Nakamura Y, Hosokawa D, Clift CL, Blaser MC, Kasai T, Weiss L, Turner ME, Billaud M, Aikawa M, Singh SA, Aikawa E

Mitochondrial Extracellular Vesicles Enhance Aortic Valve Calcification Via Carnitine O-Octanoyltransferase.
Arterioscler Thromb Vasc Biol. 2026;46(7):e324456 - PMID: 42093641 - PMCID: PMC13155380 - DOI: 10.1161/ATVBAHA.126.324456

Wang JG, Ito S, Hosokawa D, Nihira K, Decano JL, Lee LH, Higashi H, Halu A, Mattson PC, Amaral G, Abib AL, Mojcher A, Mlynarchik AK, Whelan M, Anderson DG, Aikawa E, Singh SA, Uchida S, Aikawa M

The long noncoding RNA lnc-FAM164A1-ACLY axis promotes pro-inflammatory responses in human primary macrophages: a systems approach.
Front Immunol. 2026;17:1776849 - PMID: 42148116 - PMCID: PMC13175867 - DOI: 10.3389/fimmu.2026.1776849

Pantaleao AN, Figueiredo FA, Mutarelli A, Guarçoni BV, Carvalho H, Fonseca I, Dahan S, Kang J, Sindre R, Oliveira JRS, Aikawa E, Levine RA, Nunes MCP, PRIMA Network

Improvement in left atrial strain after percutaneous mitral valvuloplasty is an independent prognostic marker in patients with rheumatic mitral stenosis.
Front Cardiovasc Med. 2026;13:1719283 - PMID: 42222110 - PMCID: PMC13219354 - DOI: 10.3389/fcvm.2026.1719283

Weiss L, Aikawa E

A novel piece to the puzzle to gain holistic understanding on calcification in CAVD: a role for NAD+ metabolism.
Eur Heart J. 2026;:ePub - PMID: 42237600 - DOI: 10.1093/eurheartj/ehag370

Amabile N, Aikawa E, Dignat-George F, Boulanger CM, Yao Y, Leroyer AS

Extracellular vesicles in atherosclerotic cardiovascular disease: mechanisms and therapeutic implications.
Eur Heart J. 2026;:ePub - PMID: 42246983 - DOI: 10.1093/eurheartj/ehag404

Lopera Higuita M, Ajenu EO, Bolger-Chen M, Olverson G, Ghavimi SAA, Lee SY, Kasai T, Michaud W, Chijioke C, Ruidas B, Pitti A, Minie N, Catricala J, Vincent D, Li S, D'Alessandro D, Aikawa E, Singh SA, Billaud M, Osho AA, Tessier SN, Rabi SA

Alternative Preservation Strategies of Donation After Circulatory Death Hearts: Effect of Cold Ischemia Time Before Normothermic Machine Perfusion.
J Am Heart Assoc. 2026;15(12):e044132 - PMID: 42261956 - PMCID: PMC13323166 - DOI: 10.1161/JAHA.125.044132

Pereira de Oliveira G, Zimmerman A, Palu CC, Tran V, Bogut G, Chidester S, Tigges J, Vega RA, Aikawa E, Jones J, Ghiran IC, Ivanov AR

Extracellular Vesicles from Glioblastoma Cells Reflect 2D vs. 3D Culture Adaptation and Resistance to Temozolomide.
Mol Cell Proteomics. 2026;:101610 - PMID: 42336206 - DOI: 10.1016/j.mcpro.2026.101610
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