Multiomic Landscape of Extracellular Vesicles in Human Carotid Atherosclerotic Plaque Reveals Endothelial Communication Networks.
Arterioscler Thromb Vasc Biol. 2025;45(7):1277-1305 - PMID: 40438929 - PMCID: PMC12188822 - DOI: 10.1161/ATVBAHA.124.322324
Decoding calcific aortic valve disease: is liver X receptor the key to lipid metabolism?
Cardiovasc Res. 2025;121(6):844-846 - PMID: 40389228 - DOI: 10.1093/cvr/cvaf080
Serine supplementation suppresses hypoxia-induced pathological retinal angiogenesis.
Theranostics. 2025;15(11):5087-5105 - PMID: 40303351 - PMCID: PMC12036884 - DOI: 10.7150/thno.105299
ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage.
Translational insights into statin-induced myotoxicity: differential impact of lipophilic and hydrophilic statins on iPSC-derived skeletal muscle cells from patients with familial hypercholesterolemia.
Toxicology. 2025;515:154159 - PMID: 40254247 - DOI: 10.1016/j.tox.2025.154159
Vascular inflammation in chronic kidney disease: the role of uremic toxins in macrophage activation.
Front Cardiovasc Med. 2025;12:1574489 - PMID: 40201789 - PMCID: PMC11975941 - DOI: 10.3389/fcvm.2025.1574489
Rheumatic heart valve disease: navigating the challenges of an overlooked autoimmune disorder.
Front Cardiovasc Med. 2025;12:1537104 - PMID: 40182432 - PMCID: PMC11966398 - DOI: 10.3389/fcvm.2025.1537104
Spermidine Enhances Mitochondrial Function and Mitigates Aortic Valve Calcification: Implications for DNA Methyltransferase-1 Activity.
JACC Basic Transl Sci. 2025;10(3):345-366 - PMID: 40139876 - PMCID: PMC12013848 - DOI: 10.1016/j.jacbts.2024.11.011
The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes: Developed by a multisociety taskforce coordinated by the Heart Valve Society (HVS) including the American Heart Association (AHA), the American College of Cardiology (ACC), the European Association for Cardio-Thoracic Surgery (EACTS), the European Society of Cardiology (ESC), The Society of Thoracic Surgeons (STS), the Australian & New Zealand Society of Cardiac & Thoracic Surgeons (ANZSCTS), the International Society for Applied Cardiovascular Biology (ISACB), the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS), the South African Heart Association (SHA), Heart Valve Voice, and Global Heart Hub.
Ann Thorac Surg Short Rep. 2025;3(1):71-85 - PMID: 40098847 - PMCID: PMC11910787 - DOI: 10.1016/j.atssr.2024.05.005
Nutrient supplementation mitigates retinal dysfunction in Acox1 knockout mice with impaired peroxisomal fatty acid oxidation.
J Adv Res. 2025;:ePub - PMID: 40049514 - DOI: 10.1016/j.jare.2025.03.004
Honoring the Life and Legacy of Dr David A. Dichek.
Arterioscler Thromb Vasc Biol. 2024;44(7):1459-1461 - PMID: 40030047 - DOI: 10.1161/ATVBAHA.124.321293
The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes.
Innovations (Phila). 2025;20(2):133-147 - PMID: 39968696 - PMCID: PMC12089684 - DOI: 10.1177/15569845241269309
The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes: Developed by a multisociety taskforce coordinated by the Heart Valve Society (HVS) including the American Heart Association (AHA), the American College of Cardiology (ACC), the European Association for Cardio-Thoracic Surgery (EACTS), the European Society of Cardiology (ESC), The Society of Thoracic Surgeons (STS), the Australian & New Zealand Society of Cardiac & Thoracic Surgeons (ANZSCTS), the International Society for Applied Cardiovascular Biology (ISACB), the International Society for Minimally Invasive Cardiothoracic Surgery (ISMICS), the South African Heart Association (SHA), Heart Valve Voice, and Global Heart Hub.
JACC Adv. 2025;4(4):101059 - PMID: 39966045 - PMCID: PMC12139239 - DOI: 10.1016/j.jacadv.2024.101059
The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes.
Circ Cardiovasc Qual Outcomes. 2025;18(3):e000128 - PMID: 39957624 - PMCID: PMC11917533 - DOI: 10.1161/HCQ.0000000000000128
The first International Consortium for Health Outcomes Measurement (ICHOM) standard dataset for reporting outcomes in heart valve disease: moving from device- to patient- centered outcomes.
Eur Heart J Qual Care Clin Outcomes. 2025;11(5):515-528 - PMID: 39957667 - PMCID: PMC12342911 - DOI: 10.1093/ehjqcco/qcae051
The First International Consortium for Health Outcomes Measurement (ICHOM) Standard Dataset for Reporting Outcomes in Heart Valve Disease: Moving From Device- to Patient-Centered Outcomes.
Eur J Cardiothorac Surg. 2025;67(2):ePub - PMID: 39957685 - PMCID: PMC11842054 - DOI: 10.1093/ejcts/ezae254
Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression.
Arterioscler Thromb Vasc Biol. 2025;45(4):481-495 - PMID: 39945065 - PMCID: PMC11936474 - DOI: 10.1161/ATVBAHA.124.321662
Endothelial FOXM1 and Dab2 promote diabetic wound healing.
JCI Insight. 2025;10(2):ePub - PMID: 39846251 - PMCID: PMC11790024 - DOI: 10.1172/jci.insight.186504
Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery.
Side- and Disease-Dependent Changes in Human Aortic Valve Cell Population and Transcriptomic Heterogeneity Determined by Single-Cell RNA Sequencing.
Integrative analysis of miRNAs and proteins in plasma extracellular vesicles of patients with familial hypercholesterolemia.
Clin Chim Acta. 2025;568:120123 - PMID: 39778611 - DOI: 10.1016/j.cca.2025.120123
In-Source Collision-Induced Dissociation (CID) Improves Higher-Energy Collisional Dissociation (HCD)-Dependent Fragmentation of ADP-Ribosyl Peptides.
Rapid Commun Mass Spectrom. 2025;39(4):e9961 - PMID: 39632390 - PMCID: PMC11617611 - DOI: 10.1002/rcm.9961
Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice.
Gene expression profiles of precursor cells identify compounds that reduce NRP1 surface expression in macrophages: Implication for drug repositioning for COVID-19.
Front Cardiovasc Med. 2024;11:1438396 - PMID: 39512370 - PMCID: PMC11541348 - DOI: 10.3389/fcvm.2024.1438396
Editorial: Global Excellence in Cardiovascular Medicine in Africa: challenges and opportunities.
Front Cardiovasc Med. 2024;11:1479281 - PMID: 39502195 - PMCID: PMC11534761 - DOI: 10.3389/fcvm.2024.1479281
Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis.
Large-Scale Proteomics Identifies Novel Biomarkers and Circulating Risk Factors for Aortic Stenosis.
J Am Coll Cardiol. 2024;83(5):577-591 - PMID: 38296402 - DOI: 10.1016/j.jacc.2023.11.021
Single-cell T cell receptor sequencing of paired tissue and blood samples reveals clonal expansion of CD8+ effector T cells in patients with calcific aortic valve disease.
PARPs and ADP-Ribosylation in Chronic Inflammation: A Focus on Macrophages.
Multimodal analytical tools to enhance mechanistic understanding of aortic valve calcification.
Am J Pathol. 2023;194(4):539-550 - PMID: 37517686 - PMCID: PMC10988764 - DOI: 10.1016/j.ajpath.2023.06.017
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves.
Circ Res. 2023;133(6):463-480 - PMID: 37555328 - PMCID: PMC10487359 - DOI: 10.1161/CIRCRESAHA.123.323027
A Combined Gas-Phase Separation Strategy for ADP-ribosylated Peptides.
J Am Soc Mass Spectrom. 2023;34(10):2136-2145 - PMID: 37589412 - PMCID: PMC10557377 - DOI: 10.1021/jasms.3c00129
CardioVision: A fully automated deep learning package for medical image segmentation and reconstruction generating digital twins for patients with aortic stenosis.
Comput Med Imaging Graph. 2023;109:102289 - PMID: 37633032 - PMCID: PMC10599298 - DOI: 10.1016/j.compmedimag.2023.102289
Tissue formation and host remodeling of an elastomeric biodegradable scaffold in an ovine pulmonary leaflet replacement model.
J Biomed Mater Res A. 2023;112(2):276-287 - PMID: 37772456 - PMCID: PMC11034854 - DOI: 10.1002/jbm.a.37622
Systematic analysis and characterization of long non-coding RNA genes in inflammatory bowel disease.
Brief Funct Genomics. 2023;23(4):395-405 - PMID: 37791426 - PMCID: PMC11260263 - DOI: 10.1093/bfgp/elad044
Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold.
Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug-Gene Networks: From Biology to Precision Therapeutics.
Circulation. 2023;148(19):1459-78 - PMID: 37850387 - PMCID: PMC10624416 - DOI: 10.1161/CIRCULATIONAHA.123.064794
Updating the paradigm: inflammation as a targetable modulator of medial vascular calcification.
Cardiovasc Res. 2023;119(13):2259-2261 - PMID: 37875065 - PMCID: PMC10597605 - DOI: 10.1093/cvr/cvad139
Discovering a Rare Smooth Muscle Cell Population Specific to Males in Ascending Aortic Aneurysm Using Spatial Transcriptomics.
Arterioscler Thromb Vasc Biol. 2023;43(12):2298-2300 - PMID: 37916413 - PMCID: PMC10842258 - DOI: 10.1161/ATVBAHA.123.320235
Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease.
Circulation. 2023;149(5):391-401 - PMID: 37937463 - PMCID: PMC10842618 - DOI: 10.1161/CIRCULATIONAHA.123.066822
FAM222A, Part of the BET-Regulated Basal Endothelial Transcriptome, Is a Novel Determinant of Endothelial Biology and Angiogenesis.
Arterioscler Thromb Vasc Biol. 2023;44(1):143-155 - PMID: 37942611 - PMCID: PMC10840377 - DOI: 10.1161/ATVBAHA.123.319909
Short-term Pre-operative Methionine Restriction Induces Browning of Perivascular Adipose Tissue and Improves Vein Graft Remodeling in Mice.
Understanding HDL Metabolism and Biology Through In Vivo Tracer Kinetics.
Arterioscler Thromb Vasc Biol. 2023;44(1):76-88 - PMID: 38031838 - PMCID: PMC10842918 - DOI: 10.1161/ATVBAHA.123.319742
Beyond the Basics: Unraveling the Complexity of Coronary Artery Calcification.
Directional Endothelial Communication by Polarized Extracellular Vesicle Release.
Circ Res. 2024;134(3):269-289 - PMID: 38174557 - PMCID: PMC10826926 - DOI: 10.1161/CIRCRESAHA.123.322993
Phosphate in Cardiovascular Disease: From New Insights Into Molecular Mechanisms to Clinical Implications.
Arterioscler Thromb Vasc Biol. 2024;44(3):584-602 - PMID: 38205639 - PMCID: PMC10922848 - DOI: 10.1161/ATVBAHA.123.319198
Macrophage Heterogeneity and Efferocytosis: Beyond the M1/M2 Dichotomy.
Circ Res. 2024;134(2):186-188 - PMID: 38236949 - PMCID: PMC10798221 - DOI: 10.1161/CIRCRESAHA.123.324011
Multi-omic Landscape of Extracellular Vesicles in Human Carotid Atherosclerotic Plaque Reveals Endothelial Communication Networks.
Carnitine O-octanoyltransferase (CROT) deficiency in mice leads to an increase of omega-3 fatty acids.
Front Mol Biosci. 2024;11:1374316 - PMID: 39076376 - PMCID: PMC11284101 - DOI: 10.3389/fmolb.2024.1374316
Timed topical dexamethasone eye drops improve mitochondrial function to prevent severe retinopathy of prematurity.
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