Turner, Mandy E.M.
Dr. Mandy Turner obtained her Bachelor of Science in Life Sciences and Mathematics (2015) from Queen’s University in Kingston, Ontario, Canada. She completed her PhD in Pharmacology and Toxicology under the supervision of Drs. Michael Adams and Rachel Holden, where she was a recipient of a Canadian Institutes of Health Research Vanier Scholarship, among others. Her research focus was in chronic kidney disease mineral bone disorder and subsequent medial vascular calcification and the generation of novel diagnostic tools thereof. Her dissertation was entitled “Translational Characterization of Acute Phosphate Disposition as it Relates to Bone and Mineral Homeostasis and Chronic Kidney Disease.”
She joined CICS in 2021 as a postdoctoral research fellow in Professor Elena Aikawa’s research group. She is working on identifying insights into extracellular vesicle mediated cellular cross talk in atherosclerosis, and potential therapeutic targets for vascular calcification regression.
Publications
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Cahalane RME, Turner ME, Clift CL, Blaser MC, Bogut G, Levy S, Kasai T, Driedonks TAP, Nolte-'t Hoen ENM, Aikawa M, Singh SA, Aikawa E
Polycarbonate Ultracentrifuge Tube Re-use in Proteomic Analyses of Extracellular Vesicles.
Clift CL, Blaser MC, Gerrits W, Turner ME, Sonawane A, Pham T, Andresen JL, Fenton OS, Grolman JM, Campedelli A, Buffolo F, Schoen FJ, Hjortnaes J, Muehlschlegel JD, Mooney DJ, Aikawa M, Singh SA, Langer R, Aikawa E
Intracellular proteomics and extracellular vesiculomics as a metric of disease recapitulation in 3D-bioprinted aortic valve arrays.
Turner ME, Beck L, Hill Gallant KM, Chen Y, Moe OW, Kuro-O M, Moe S, Aikawa E
Phosphate in Cardiovascular Disease: From New Insights Into Molecular Mechanisms to Clinical Implications.
Turner ME, Aikawa E
Updating the paradigm: inflammation as a targetable modulator of medial vascular calcification.
Blaser MC, Buffolo F, Halu A, Turner ME, Schlotter F, Higashi H, Pantano L, Clift CL, Saddic LA, Atkins SK, Rogers MA, Pham T, Vromman A, Shvartz E, Sukhova GK, Monticone S, Camussi G, Robson SC, Body SC, Muehlschlegel JD, Singh SA, Aikawa M, Aikawa E
Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis.
Bartoli-Leonard F, Chelvanambi S, Pham T, Turner ME, Blaser MC, Caputo M, Aikawa M, Pang A, Muehlschlegel J, Aikawa E
Single-cell T cell receptor sequencing of paired tissue and blood samples reveals clonal expansion of CD8+ effector T cells in patients with calcific aortic valve disease.
Bartoli-Leonard F, Zimmer J, Sonawane AR, Perez K, Turner ME, Kuraoka S, Pham T, Li F, Aikawa M, Singh S, Brewster L, Aikawa E
NLRP3 Inflammasome Activation in Peripheral Arterial Disease.
Bartoli-Leonard F, Turner ME, Zimmer J, Chapurlat R, Pham T, Aikawa M, Pradhan AD, Szulc P, Aikawa E
Elevated lipoprotein(a) as a predictor for coronary events in older men.
