Lee, Lang Ho
Dr. Lang Ho Lee has joined to CICS since August, 2015 after completing his PhD degree in the Genome Science and Technology at the University of Tennessee and Oak Ridge National Laboratory (UT-ORNL). He studied bioinformatics during PhD and developed analysis pipeline and novel algorithms for metaproteomics data analysis. At CICS, he has been working as a bioinformatician who is in charge of proteomics data analysis and analyze various clinical data.
Publications
ShowGoto S, Rogers MA, Blaser MC, Higashi H, Lee LH, Schlotter F, Body SC, Aikawa M, Singh SA, Aikawa E
Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification.
Higashi H, Maejima T, Lee LH, Yamazaki Y, Hottiger MO, Singh SA, Aikawa M
A study into the ADP-ribosylome of IFN-γ-stimulated THP-1 human macrophage-like cells identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-ribosylation.
J Proteome Res. 2019;18(4):1607-1622 - PMID: 30848916 - PMCID: PMC6456868 - DOI: 10.1021/acs.jproteome.8b00895
Higashi H, Maejima T, Lee LH, Yamazaki Y, Hottiger MO, Singh SA, Aikawa M
A study into the ADP-ribosylome of IFN-γ-stimulated THP-1 human macrophage-like cells identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-ribosylation.
J Proteome Res. 2019;18(4):1607-1622 - PMID: 30848916 - PMCID: PMC6456868 - DOI: 10.1021/acs.jproteome.8b00895
Creager MD, Hohl T, Hutcheson JD, Moss AJ, Schlotter F, Blaser MC, Park MA, Lee LH, Singh SA, Alcaide-Corral CJ, Tavares AAS, Newby DE, Kijewski MF, Aikawa M, Di Carli M, Dweck MR, Aikawa E
18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images.
Circ Cardiovasc Imaging. 2019;12(1):e007835 - PMID: 30642216 - PMCID: PMC6338081 - DOI: 10.1161/CIRCIMAGING.118.007835
Lee LH, Halu A, Morgan S, Iwata H, Aikawa M, Singh SA
XINA: A Workflow for the Integration of Multiplexed Proteomics Kinetics Data with Network Analysis.
J Proteome Res. 2018;18(2):775-781 - PMID: 30370770 - DOI: 10.1021/acs.jproteome.8b00615
van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes J, Langer R, Aikawa E
Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.
Nanomaterials (Basel). 2018;8(5):ePub - PMID: 29751516 - PMCID: PMC5977310 - DOI: 10.3390/nano8050296
Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E
Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Circulation. 2018;138(4):377-393 - PMID: 29588317 - PMCID: PMC6160370 - DOI: 10.1161/CIRCULATIONAHA.117.032291
Lee LH, Andraski AB, Pieper B, Higashi H, Sacks FM, Aikawa M, Singh SA
Automation of PRM-dependent D3-Leu tracer enrichment in HDL to study the metabolism of apoA-I, LCAT and other apolipoproteins.