Delwarde, Constance

Constance Delwarde is a Research Fellow at the Center for Interdisciplinary Cardiovascular Sciences. After completing her Master’s degree, she obtained a PhD in Mitral Valve Prolapse from Nantes Université, France. Constance was awarded the 2022 best fundamental research thesis from the French Society of Cardiology. She used multimodality imaging, transcriptomics, epigenetics, molecular, and cellular approaches to establish the involvement of immune cells and macrophages in the pathophysiology of non-syndromic mitral valve prolapse in rats.

During her PhD, Constance was awarded the Mitacs Globalink Grant, which allowed her to explore North American laboratory culture and organization. She then decided to travel to the States to work as a postdoctoral research fellow under the mentorship of Dr. Masanori Aikawa, with interest in macrophage heterogeneity and cardiovascular diseases. Her work primarily focuses on identifying mechanisms underlying the higher incidence of cardiovascular events in HIV-treated aging patients.