Goettsch, Claudia

Goettsch, Claudia

Dr. Claudia Goettsch studied nutrition sciences at the University of Jena (Germany), and did her PhD thesis in the Department of Vascular Endothelium and Microcirculation at the Medical Faculty of the University of Technology Dresden , Germany. During this time she studied different NADPH oxidase (Nox) isoforms as potential molecular sources of reactive oxygen species in human endothelial cells. Dr. Goettsch was enrolled at the PhD program “Metabolism and Endothelium” of the Dresden Medical Faculty and finished her PhD thesis “Regulation of oxidative stress by biomechanical forces and high-fat diet in the cardiovascular system” in 2007.
She was awarded the Carl GustavCarus Award for the best PhD thesis in 2007.
Dr. Goettsch did her first postdoc in the bone vascular lab of Prof. Lorenz Hofbauer (Dresden, Germany). There she systematically extended her research and knowledge from vascular biology to bone metabolism.The major scientific goal and interest was to uncover the mechanisms underlying the arterial calcification-osteoporosis syndrome, which is of key interest given the high coincidence of osteoporosis and vascular calcification in the aging population. As part of that research she focused on oxidative stress, in particular stress cause by oxidized lipoproteins, and investigated the role of NFATs and miRNAs during osteogenic processes within the vascular wall. In 2009 Dr. Goettsch was given a Research Award “Dresdner Cardiovascular Days” (Germany) and she received a Young Investigator Award from the American Society for Bone and Mineral Research (ASBMR). Her work on miRNAs in calcification processes received the Young Investigator Award of the German Bone Society.
Dr. Goettsch has been a postdoctoral research fellow at CICS since June 2011. She focuses primarily on the identification of common mediators and mechanisms of both arterial calcification and bone remodeling. Dr. Goettsch’s major scientific goal is to identify targets which prevent cardiovascular calcification.

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