Iwata, Hiroshi
Publications
ShowLee LH, Halu A, Morgan S, Iwata H, Aikawa M, Singh SA
XINA: A Workflow for the Integration of Multiplexed Proteomics Kinetics Data with Network Analysis.
J Proteome Res. 2018;18(2):775-781 - PMID: 30370770 - DOI: 10.1021/acs.jproteome.8b00615
Halu A, Wang JG, Iwata H, Mojcher A, Abib AL, Singh SA, Aikawa M, Sharma A
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation.
Goettsch C, Iwata H, Hutcheson JD, O'Donnell CJ, Chapurlat R, Cook NR, Aikawa M, Szulc P, Aikawa E
Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.
Arterioscler Thromb Vasc Biol. 2017;37(5):1005-1011 - PMID: 28279970 - PMCID: PMC5407935 - DOI: 10.1161/ATVBAHA.116.308932
Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
Kramann R, Goettsch C, Wongboonsin J, Iwata H, Schneider RK, Kuppe C, Kaesler N, Chang-Panesso M, Machado FG, Gratwohl S, Madhurima K, Hutcheson JD, Jain S, Aikawa E, Humphreys BD
Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease.
Cell Stem Cell. 2016;19(5):628-642 - PMID: 27618218 - PMCID: PMC5097006 - DOI: 10.1016/j.stem.2016.08.001
Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabási AL, Loscalzo J
Endophenotype Network Models: Common Core of Complex Diseases.
Goettsch C, Iwata H, Aikawa E
Parathyroid hormone: critical bridge between bone metabolism and cardiovascular disease.
Arterioscler Thromb Vasc Biol. 2014;34(7):1333-5 - PMID: 24951650 - PMCID: PMC4094346 - DOI: 10.1161/ATVBAHA.114.303637
Iwata H, Aikawa M
Liver-Artery Interactions via the Plasminogen-CD36 Axis in Macrophage Foam Cell Formation: New Evidence for the Role of Remote Organ Crosstalk in Atherosclerosis.
Circulation. 2013;127(11):1173-6 - PMID: 23509031 - DOI: 10.1161/CIRCULATIONAHA.113.001461
Iwata A, Higuchi Y, Kimura D, Okamoto K, Arai S, Iwata H, Fuchioka S
Quick lateral movements of the trunk in a seated position reflect mobility and activities of daily living (ADL) function in frail elderly individuals.
Arch Gerontol Geriatr. 2012;56(3):482-6 - PMID: 23270712 - DOI: 10.1016/j.archger.2012.12.002
Iwata H, Nagai R
Novel immune signals and atherosclerosis.
Curr Atheroscler Rep. 2012;14(5):484-90 - PMID: 22864646 - DOI: 10.1007/s11883-012-0267-7
Semba H, Kinugawa K, Takeda N, Shiga T, Nishimura G, Inajima T, Uchino Y, Iwata H, Hasumi E, Abe H, Terada Y, Yonenaga A, Hirata Y, Nagai R
Preliminary report of tolvaptan treatment in Japanese patients with heart failure.
Int Heart J. 2012;53(1):72-4 - PMID: 22398679 - DOI: 10.1536/ihj.53.72
Kohro T, Iwata H, Fujiu K, Manabe I, Fujita H, Haraguchi G, Morino Y, Oguri A, Ikenouchi H, Kurabayashi M, Ikari Y, Isobe M, Ohe K, Nagai R
Development and implementation of an advanced coronary angiography and intervention database system.
Int Heart J. 2012;53(1):35-42 - PMID: 22398674 - DOI: 10.1536/ihj.53.35
Myojo M, Iwata H, Kohro T, Sato H, Kiyosue A, Ando J, Sawaki D, Takahashi M, Fujita H, Hirata Y, Nagai R
Prognostic implication of macrocytosis on adverse outcomes after coronary intervention.
Atherosclerosis. 2011;221(1):148-53 - PMID: 22222418 - DOI: 10.1016/j.atherosclerosis.2011.11.044
Higashikuni Y, Sainz J, Nakamura K, Takaoka M, Enomoto S, Iwata H, Tanaka K, Sahara M, Hirata Y, Nagai R, Sata M
The ATP-Binding Cassette Transporter ABCG2 Protects Against Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure by Promoting Angiogenesis and Antioxidant Response.
Arterioscler Thromb Vasc Biol. 2011;32(3):654-61 - PMID: 22116099 - DOI: 10.1161/ATVBAHA.111.240341
Ikutomi M, Matsumura T, Iwata H, Nishimura G, Ishizaka N, Hirata Y, Ono M, Nagai R
Giant tumorous lesions (correction of legions) surrounding the right coronary artery associated with immunoglobulin-G4-related systemic disease.
Cardiology. 2011;120(1):22-6 - PMID: 22094884 - DOI: 10.1159/000332996
Kimura K, Takenaka K, Ebihara A, Uno K, Iwata H, Sata M, Kohro T, Morita H, Yatomi Y, Nagai R
Reproducibility and diagnostic accuracy of three-layer speckle tracking echocardiography in a swine chronic ischemia model.
Echocardiography. 2011;28(10):1148-55 - PMID: 21967399 - DOI: 10.1111/j.1540-8175.2011.01517.x
Higashikuni Y, Takaoka M, Iwata H, Tanaka K, Hirata Y, Nagai R, Sata M
Aliskiren in combination with valsartan exerts synergistic protective effects against ventricular remodeling after myocardial infarction in mice.
Hypertens Res. 2011;35(1):62-9 - PMID: 21833001 - DOI: 10.1038/hr.2011.136
Hasumi E, Iwata H, Saito K, Fujiu K, Ando J, Imai Y, Fujita H, Hirata Y, Nagai R
Diagnostic efficacy of coronary CT angiography as a follow-up modality for procedure-related coronary dissection.
Int Heart J. 2011;52(4):240-2 - PMID: 21828951 - DOI: 10.1536/ihj.52.240
Matsubara TJ, Iwata H, Shiga T, Hatano M, Yao A, Ono M, Kinugawa K, Hirata Y, Nagai R
Progressive coronary artery-pulmonary artery fistula after size-mismatch cardiac transplantation.
ASAIO J. 2011;57(4):346-7 - PMID: 21508827 - DOI: 10.1097/MAT.0b013e3182198b7a
Iwata H, Manabe I, Fujiu K, Yamamoto T, Takeda N, Eguchi K, Furuya A, Kuro-o M, Sata M, Nagai R
Bone marrow-derived cells contribute to vascular inflammation but do not differentiate into smooth muscle cell lineages.
Circulation. 2010;122(20):2048-57 - PMID: 21041690 - DOI: 10.1161/CIRCULATIONAHA.110.965202
Higashikuni Y, Sainz J, Nakamura K, Takaoka M, Enomoto S, Iwata H, Sahara M, Tanaka K, Koibuchi N, Ito S, Kusuhara H, Sugiyama Y, Hirata Y, Nagai R, Sata M
The ATP-binding cassette transporter BCRP1/ABCG2 plays a pivotal role in cardiac repair after myocardial infarction via modulation of microvascular endothelial cell survival and function.
Arterioscler Thromb Vasc Biol. 2010;30(11):2128-35 - PMID: 20829509 - DOI: 10.1161/ATVBAHA.110.211755
Iwata H, Sata M, Ando J, Fujita H, Morita T, Sawaki D, Takahashi M, Hirata Y, Takanashi S, Tabata M, Hirata Y, Nagai R
Impact of primitive cells in intracoronary thrombi on lesion prognosis: temporal analysis of cellular constituents of thrombotic material obtained from patients with acute coronary syndrome.
Heart. 2010;96(10):748-55 - PMID: 20448125 - DOI: 10.1136/hrt.2009.181040
Kataoka K, Nannya Y, Iwata H, Seo S, Kumano K, Takahashi T, Nagai R, Kurokawa M
Plasma brain natriuretic peptide is associated with hepatic veno-occlusive disease and early mortality after allogeneic hematopoietic stem cell transplantation.
Bone Marrow Transplant. 2010;45(11):1631-7 - PMID: 20173786 - DOI: 10.1038/bmt.2010.26
Iwata H, Nakamura K, Sumi M, Ninomiya M, Sakai Y, Hirata Y, Akaike M, Igarashi T, Takamoto S, Nagai R, Sata M
Local delivery of synthetic prostacycline agonist augments collateral growth and improves cardiac function in a swine chronic cardiac ischemia model.
Life Sci. 2009;85(5-6):255-61 - PMID: 19527738 - DOI: 10.1016/j.lfs.2009.06.002
Iwata H, Ako J, Nagai R
Recurrence of late-acquired incomplete stent apposition following sirolimus-eluting stent implantation.
J Invasive Cardiol. 2008;20(9):E265-8 - PMID: 18762685
Iwata H, Sata M
Origin of cells that contribute to neointima growth.
Circulation. 2008;117(24):3060-1 - PMID: 18559712 - DOI: 10.1161/CIRCULATIONAHA.108.782961
Nakamura K, Sata M, Iwata H, Sakai Y, Hirata Y, Kugiyama K, Nagai R
A synthetic small molecule, ONO-1301, enhances endogenous growth factor expression and augments angiogenesis in the ischaemic heart.
Clin Sci (Lond). 2007;112(12):607-16 - PMID: 17263691 - DOI: 10.1042/CS20060301
Iwata H, Sata M
Potential contribution of bone marrow-derived precursors to vascular repair and lesion formation: lessons from animal models of vascular diseases.
Front Biosci. 2007;12:4157-67 - PMID: 17485364 - DOI: 10.2741/2377
Takeda N, Manabe I, Shindo T, Iwata H, Iimuro S, Kagechika H, Shudo K, Nagai R
Synthetic retinoid Am80 reduces scavenger receptor expression and atherosclerosis in mice by inhibiting IL-6.
Arterioscler Thromb Vasc Biol. 2006;26(5):1177-83 - PMID: 16484594 - DOI: 10.1161/01.ATV.0000214296.94849.1c
Iwata H, Matsuo K, Hara S, Takeuchi K, Aoyama T, Murashige N, Kanda Y, Mori S, Suzuki R, Tachibana S, Yamane M, Odawara M, Mutou Y, Kami M
Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.
Cancer Sci. 2006;97(2):133-8 - PMID: 16441424 - PMCID: PMC11159005 - DOI: 10.1111/j.1349-7006.2006.00153.x
Fujiu K, Manabe I, Ishihara A, Oishi Y, Iwata H, Nishimura G, Shindo T, Maemura K, Kagechika H, Shudo K, Nagai R
Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5.
Circ Res. 2005;97(11):1132-41 - PMID: 16224062 - DOI: 10.1161/01.RES.0000190613.22565.13
Murashige N, Kami M, Iwata H, Kishi Y, Matsuo K
No relationship between hepatitis C infection and risk of myeloid malignancy.
Haematologica. 2005;90(4):572-4 - PMID: 15820965
Iwata H, Sata M, Nagai R
Complete aspiration of thrombi from an occluded coronary artery.
Iimuro S, Shindo T, Moriyama N, Amaki T, Niu P, Takeda N, Iwata H, Zhang Y, Ebihara A, Nagai R
Angiogenic effects of adrenomedullin in ischemia and tumor growth.
Circ Res. 2004;95(4):415-23 - PMID: 15242974 - DOI: 10.1161/01.RES.0000138018.61065.d1
Hamaki T, Kami M, Kishi A, Kusumi E, Kishi Y, Iwata H, Miyakoshi S, Ueyama J, Morinaga S, Taniguchi S, Ohara K, Muto Y
Vesicles as initial skin manifestation of disseminated fusariosis after non-myeloablative stem cell transplantation.
Leuk Lymphoma. 2004;45(3):631-3 - PMID: 15160931 - DOI: 10.1080/1042819031000151941
Iwata H, Matsuo K, Takeuchi K, Kishi Y, Murashige N, Kami M
High incidences of malignant lymphoma in patients infected with hepatitis B or hepatitis C virus.
Haematologica. 2004;89(3):368-70 - PMID: 15020283
Niu P, Shindo T, Iwata H, Iimuro S, Takeda N, Zhang Y, Ebihara A, Suematsu Y, Kangawa K, Hirata Y, Nagai R
Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage.
Circulation. 2004;109(14):1789-94 - PMID: 14967720 - DOI: 10.1161/01.CIR.0000118466.47982.CC
Kami M, Hamaki T, Kusumi E, Iwata H, Ueyama J, Morinaga S, Miyakoshi S, Taniguchi S, Muto Y
Recurrent psychotic episodes in a patient who received rituximab for the treatment of non-Hodgkin's lymphoma.
Hematol J. 2004;5(1):90 - PMID: 14745437 - DOI: 10.1038/sj.thj.6200305
Niu P, Shindo T, Iwata H, Ebihara A, Suematsu Y, Zhang Y, Takeda N, Iimuro S, Hirata Y, Nagai R
Accelerated cardiac hypertrophy and renal damage induced by angiotensin II in adrenomedullin knockout mice.
Hypertens Res. 2003;26(9):731-6 - PMID: 14620929 - DOI: 10.1291/hypres.26.731
Iwata H, Aoyama T, Kami M
Effects of pravastatin in the elderly.
Ann Intern Med. 2002;136(11):W2 - PMID: 12044146 - DOI: 10.7326/0003-4819-136-11-200206040-w2
Iwata H, Aoyama T, Kusumi E, Hamaki T, Kami M
Limitations of a meta-analysis investigating the association between cancer and statin use.
Am J Med. 2002;112(2):157-8 - PMID: 11835959 - DOI: 10.1016/s0002-9343(01)01040-3
Kami M, Kishi Y, Hamaki T, Maruta Y, Kusumi E, Iwata H, Ueyama JI, Miyakoshi S, Morinaga SI, Mutou Y
A prospective surveillance of nosocomial respiratory syncytial virus infection in a hematology ward: a single-center experience in Japan.
Int J Hematol. 2001;74(3):357-9 - PMID: 11721978 - DOI: 10.1007/BF02982076
Iwata H, Kami M, Hori A, Hamaki T, Takeuchi K, Mutou Y
An autopsy-based retrospective study of secondary thrombotic thrombocytopenic purpura.
Haematologica. 2001;86(6):669-70 - PMID: 11418383
Shibata S, Kami M, Kanda Y, Machida U, Iwata H, Kishi Y, Takeshita A, Miyakoshi S, Ueyama J, Morinaga S, Mutou Y
Acute adrenal failure associated with fluconazole after administration of high-dose cyclophosphamide.
Am J Hematol. 2001;66(4):303-5 - PMID: 11279645 - DOI: 10.1002/ajh.1063
Iwata H, Kami M, Kishi Y, Oki Y, Tanaka Y, Takeuchi K, Yamazaki I, Suzuki R, Morinaga S, Mutou Y
Limitations of the diagnostic criteria for minimally differentiated acute myeloid leukemia (AML-MO)
Leukemia. 2000;14(11):2013-4 - PMID: 11069040 - DOI: 10.1038/sj.leu.2401927